The current global epidemic of new synthetic drugs is constantly changing, and manufacturers evade legal supervision through chemical structure modification, resulting in the emergence of new varieties in an endless stream. The following are some of the more popular new synthetic drugs and related information in recent years： ### 1. **Synthetic Cannabinoids (Synthetic Cannabinoids)** -**Commonly known as**: Spice, K2, spice, magic smoke -**Features**: The chemical structure simulates THC in cannabis, but the effect is stronger and unpredictable, often leading to epilepsy, insanity and even death. -**New variants**: Such as ADB-CHMINACA, 5F-MDMB-PICA, etc., THESE new derivatives are extremely effective and some are not under international control. ### 2. **Cathinones (Cathinones)** -**Commonly known as**: Bath Salts, Mephedrone, Mephedrone, Mephedrone, Mephedrone, Mephedrone, Mephedrone, Mephedrone -**Features**: As a stimulant, it causes aggressive behavior and cardiovascular problems. In recent years, new variants such as α-PVP (“zombie medicine”) and 3-MMC have emerged, especially in Europe, America and Southeast Asia. ### 3. **Fentanyl Analogues (Fentanyl Analogues)** -**Common types**: Carfentanil (Carfentanil), Acryloylfentanyl (Acryloylfentanyl) -**Hazard**: The potency is 50-100 times that of heroin, and it can be fatal in very low doses. It is often mixed with counterfeit prescription drugs (such as oxycontin) or heroin, which has led to a surge in overdose deaths in North America. ### 4. **Phenethylamine hallucinogens (Phenethylamines)** -**Representative substances**: NBOMe series (such as 25I-NBOMe), 2C-B-FLY -**Risk**: As a cheap alternative to LSD, it is more toxic and may cause acute poisoning and organ failure. ### 5. **Synthetic Opiate (Novel Synthetic Opiate)** -**For example**: Isobutyrylfentanyl (Isobutyrylfentanyl), Valerylfentanyl (Valerylfentanyl) -*****: Some varieties are not controlled by international conventions and circulate through the dark Web. ### 6. **New type of sedative (Benzodiazepine Analogues)** -**Such as**: Flunitrazolam (Flunitrazolam), Clonazolam (Clonazolam) -**Mode of abuse**: It is often used in combination with opiate drugs to increase the risk of respiratory depression. ### 7. **Synthetic drugs in electronic cigarettes** -**Form**: Synthetic cannabinoids or cassidone are dissolved in electronic cigarette oil, which is highly concealable and attracts young people. ### Epidemic Causes and Challenges： -**Legal lag**: Most countries adopt a list of control systems, and new types of structural drugs can temporarily evade supervision. -**Easy to manufacture**: It can be synthesized in a small laboratory, and raw materials are easy to obtain. -**Dark Web transactions**: Through encrypted networks and cryptocurrency transactions, it is more difficult to enforce the law. ### Regional differences： -**North America**: The crisis of fentanyl analogues is serious. -**Europe**: Cassidones and synthetic cannabinoids are popular. -**Asia**: Methamphetamine (methamphetamine) still dominates, but the penetration of new synthetic drugs has increased. ### Warning： The harm of new synthetic drugs far exceeds that of traditional drugs. Due to the complex composition and difficult dose control, it can easily lead to acute poisoning or long-term mental damage. The public needs to be vigilant and avoid contact with substances of unknown origin. Governments are strengthening international cooperation and dynamic governance to meet the challenges.