It is theoretically possible to improve or "enhance" human sensory functions (such as improving visual or auditory sensitivity) using gene editing technology, but it is still in a very early stage of exploration and faces many technical, ethical and safety challenges. The following are some related thinking directions and technical difficulties: 1. Scientific basis and research objectives a. Identification of key genes: First, it is necessary to clarify which genes play a key role in controlling sensory development and function. For example, in terms of vision, we may focus on genes involved in the development and functional regulation of retinal photoreceptors (such as rods and cones), while in terms of hearing, we may involve genes that regulate the development, function and regeneration of cochlear hair cells. b. Fine-tuning function: Improving sensory sensitivity is usually not just a matter of "more", but also requires fine-tuning the capture, transmission and processing of signals. Whether gene editing can achieve the desired changes requires a holistic understanding and comprehensive consideration at the cellular level and the neural network level. 2. Feasible gene editing methods a. CRISPR/Cas9 and other new tools: Currently, gene editing tools such as CRISPR/Cas9 have been used in a variety of therapeutic studies. In theory, by precisely targeting functional variants in or out, the expression level of the target gene or the protein function can be changed, which may improve the detection ability of a specific sense organ. b. Gene regulation and expression enhancement: In addition to simple gene modification, gene activation systems (such as CRISPRa) or gene suppression systems (such as CRISPRi) can also be considered to regulate the expression level of key sensory function genes without destroying the genome structure. 3. Application examples and exploration directions a. Vision: Some animal studies have tried to improve visual ability in low-light environments by introducing exogenous photosensitive proteins (such as engineered rhodopsin); in addition, there are also studies focusing on how to repair retinal dysfunction caused by genetic diseases. b. Auditory field: In the treatment of hearing loss, some experiments are trying to use gene editing to restore the function of damaged hair cells or promote hair cell regeneration, thereby improving auditory sensitivity. In theory, if the performance of hair cells can be enhanced or the number can be increased, the efficiency of capturing auditory signals may be improved. 4. Technical difficulties and safety issues a. Off-target effects: Any gene editing operation may produce unexpected gene modifications outside the intended target, which may cause unforeseen physiological consequences when changing the function of complex systems (such as sensory organs). b. Systemic balance: The human sensory system has evolved over a long period of time, and any "enhancement" is very likely to disrupt the system balance and produce side effects such as oversensitivity (more susceptible to noise damage or light stimulation). c. Long-term stability and controllability: Even if the initial effect is ideal, it is necessary to ensure stable expression and long-term effects after gene modification, which places extremely high demands on technical level and clinical monitoring. 5. Ethical, legal and social considerations a. Ethical controversy: There is an essential difference between "enhanced" gene editing of healthy individuals and therapeutic gene editing. Ethicists, scientists and the public still have widespread controversy over the "optimization" of human sensory functions and the possible unfairness (such as the social stratification that "gene enhancement" may bring). b. Regulatory supervision: At present, most parts of the world are cautious or even prohibitive about human germline or germline gene editing. Any such attempt must be under strict supervision and after sufficient demonstration before clinical application. In summary, the use of gene editing technology to change human sensory function (such as improving visual or auditory sensitivity) is a highly promising but challenging topic. Most of the current research is focused on the field of disease treatment. Attempts to "enhance" the sensory abilities of healthy people not only have huge technical uncertainties, but also face severe tests at the ethical and legal levels. To achieve this goal in the future, it is necessary to carefully advance related research based on a deep understanding of sensory physiology, gene regulatory networks, and global system impacts, after rigorous scientific experiments and ethical assessments.