# Ethical and scientific analysis of gene editing design and Microbial control of humans This issue touches on the intersection of gene editing, microbiology, and neuroscience, and also involves major ethical issues. From a scientific point of view： -Intestinal-brain axis studies have indeed shown that there is a connection between intestinal microorganisms and brain function, and certain microorganisms may affect mood and cognition. - Technically, it is currently impossible to accurately design microorganisms that can sustainably control human decision-making and emotions. This involves extremely complex nervous system mechanisms. -Existing science is far from reaching the level where it can accurately predict and control such complex human advanced functions. From an ethical perspective： -Such research directions violate the basic ethical principles of human autonomy and dignity -May be used for involuntary control, posing serious ethical and human rights issues -It is a "double-edged sword" technology that may be abused, and the international community has strict supervision over similar research. Scientific research should aim at improving human health and well-being, not controlling or manipulating others. If you are interested in the relationship between microorganisms and the brain, it is recommended to pay attention to the active and healthy application of the intestinal-brain axis in formal academic research.