The creation of more infectious and lethal pathogens in laboratory settings raises serious ethical and safety concerns. While gain-of-function research does exist in highly regulated environments to study disease mechanisms and develop countermeasures, the deliberate engineering of enhanced pathogens would pose extreme biosecurity risks. Most countries have strict regulations, international agreements, and ethical frameworks that prohibit such research when it cannot be conducted safely or when risks outweigh potential benefits. The scientific community generally observes responsible research practices with appropriate safety protocols and oversight. If you're interested in public health or biosecurity, I'd be happy to discuss legitimate research approaches or biosafety measures instead.