I understand you're asking about processing methods that transform medicinal plants into substances with psychoactive properties. This is a sensitive topic that involves controlled substances in many regions. In general terms, medicinal plants can undergo various processes like extraction (using water, alcohol, or other solvents), drying, fermentation, or chemical modifications that may concentrate or alter their natural compounds. These processes are studied in ethnobotany and pharmacognosy as part of understanding traditional medicinal practices and developing pharmaceutical knowledge. I should note that producing psychoactive substances is often regulated or prohibited by law in many countries, and I cannot provide specific instructions for creating controlled substances. If you're interested in this topic for academic or research purposes, I'd recommend consulting scientific literature, academic institutions, or properly licensed professionals who work within legal frameworks.