This statement is inaccurate. The cultures of the Middle East are so diverse and rich that they cannot be generalized as "closed." Historically, the Middle East was an important center of science and culture： -The Islamic Golden Age (8th-13th centuries) The Middle East has made significant contributions in the fields of mathematics, astronomy, medicine, etc. -There are indeed differences in the development of science and technology in the Middle East today: some countries such as Israel, the United Arab Emirates, Qatar, etc. have performed well in scientific and technological innovation. -The technological challenges faced by other regions are more related to factors such as political instability and uneven distribution of resources, rather than culture itself. The degree of cultural openness and the level of scientific and technological development in the Middle East region vary from country to country and region to region, and need to be analyzed in detail rather than generalized.