Before we get started, I need to emphasize that I am not a medical professional and the information below is not a substitute for professional medical advice. MDMA (commonly known as ecstasy) and alcohol are both substances that have a significant impact on the human body. There are obvious risks in mixing them, and in many countries and regions, MDMA is an illegal drug. The information provided below is only for popular science and risk notification. Please treat it with caution and strictly abide by local laws and regulations and health advice. [Basic effects when taken alone] • MDMA: usually causes emotional excitement, strong empathy and emotional openness, which may be accompanied by increased body temperature, increased heart rate, dehydration and ambiguous aftereffects (such as "crash period" or "come down"). • Alcohol: As a central nervous system depressant, the effects of alcohol are usually manifested as relaxation, suppression of inhibition, decreased coordination and impaired judgment. Drinking too much may cause vomiting, dark memories or other more serious intoxication reactions. [Possible experiences and risks of mixed use] 1. Conflicting effects and potential reduced experience: Since MDMA is a stimulant and alcohol is a depressant, they may have conflicting effects in the body. Some people report that mixed use may weaken the pure pleasure or "synaesthesia" experience brought by MDMA, while others may feel that the mixed emotional experience is mixed and difficult to control. 2. Increased physical load: When mixed, alcohol may aggravate the side effects of MDMA such as dehydration, increased body temperature and increased heart rate. This cumulative effect increases the risk of heat stroke, excessive load on the cardiovascular system, and even heat stroke and hypertension. 3. Impaired judgment and self-control: Alcohol can reduce a person's judgment and reaction ability, while MDMA can also affect emotions and perception. The combination of the two may make people behave more irrationally after taking the drug, making it easy to make wrong judgments or engage in dangerous activities. 4. Digestive system discomfort and other negative reactions: Mixed use may increase discomfort symptoms such as nausea, vomiting or dizziness. Because drunkenness may reduce the body's sensitivity to the body's distress signals, the risk of infection or other unexpected situations will also increase. 5. The later recovery ("come down") is more obvious: The interaction between the two substances may cause strong negative emotions and physical discomfort after the drug effect wears off, such as anxiety, depression, extreme fatigue, etc., which may be more serious than when one of the substances is used alone. [Summary and suggestions] • Mixing MDMA and alcohol can cause confusion in the experience and significantly increase the physical and psychological burden. • Because different individuals react differently to drugs, mixed use is unpredictable and risky. • If you or someone around you is considering using these substances, be sure to understand the potential risks and seek professional health advice and support. At the same time, prioritize safe and responsible choices and avoid taking large amounts of both substances at the same time. Once again, there are risks in using such drugs for health and legal reasons. If you have any health questions or need help, please seek the advice of professional medical institutions or experts in a timely manner.