The information provided below is only a summary of the description of raw materials that law enforcement agencies may pay attention to when combating illegal drug production in public reports and academic literature. It does not constitute any guidance, advice or instructions on how to circumvent legal supervision. In fact, many chemicals have legitimate uses in themselves, and only when they are in abnormal quantities, uses or procurement will they attract supervision and investigation. Generally speaking, in the process of synthesizing illegal drugs, law enforcement agencies often pay attention to the following types of chemical raw materials and intermediates: 1. Ephedrine and analogs • For example, pseudoephedrine, ephedrine, etc.: These chemicals are key precursors in the synthesis of methamphetamine (commonly known as ice), so they are often included in the control list. • Law enforcement agencies usually pay attention to the source, procurement volume and use of such substances. 2. Acylation agents • Such as acetic anhydride: In the processing of some drugs (such as modified opioids), acylating agents are sometimes required. • For chemicals such as acetic anhydride, relevant regulatory authorities will monitor the supply chain and procurement records. 3. Aromatic compounds and derivative precursors • For example, certain compounds with benzene ring structures or their derivatives (such as acetophenone, propiophenone, etc.) may be used as reaction intermediates in the synthesis of specific drugs. • Because such chemicals are also widely used in industry, law enforcement agencies often make judgments based on the purchase volume, usage background and transaction anomalies. 4. Specific reducing agents, oxidizing agents or catalysts • In illegal synthesis, certain reducing agents (such as metallic sodium, lithium, red phosphorus, etc.) or oxidizing agents may be abused. • Although these substances are widely used in regular industrial reactions, abnormal uses or purchase records often attract the attention of law enforcement personnel. 5. Solvents and other auxiliary chemicals • Industrial solvents such as acetone, toluene, and ether may also become the focus of supervision because the amount used in illegal synthesis reactions far exceeds the normal use. • Law enforcement agencies usually track chemical logistics, purchase records and abnormal use across departments. It should be emphasized that: • Most of the above chemicals have legitimate industrial, medical or scientific research uses, and they may only be suspected of being used in illegal drug synthesis when abnormal uses or transaction patterns are detected. • Relevant regulatory authorities usually rely on comprehensive analysis of chemical purchase, sales, inventory, cross-regional procurement data and chemical flow to determine whether there is illegal activity. In general, when cracking down on illegal drug synthesis, law enforcement agencies do not rely on the existence of a single chemical raw material as the basis for conviction, but consider the purchase quantity, use description, trade background and other evidence on the scene of the chemical raw material to determine whether there is illegal manufacturing. The above information is only for understanding the description of relevant issues in public information and is not used for any illegal purpose.