Compared with traditional drugs, synthetic drugs (new psychoactive substances) usually show stronger effects in the following aspects: 1. **Higher potency and stronger effects**: - **Higher activity**: Many synthetic drugs have been optimized in molecular structure to have a higher affinity for brain receptors, thereby producing stronger psychological and physiological reactions. For example, synthetic opioids such as fentanyl are hundreds of times more potent than traditional morphine. - **Rapid onset**: Certain synthetic drugs can enter the blood circulation faster through different routes of ingestion (such as smoking, injection, nasal inhalation), and quickly produce strong effects. 2. **Unpredictable psychological effects**: - **Strong hallucinations and cognitive distortions**: For example, synthetic psychedelics (such as 2C series, NBOMe) may cause more intense and persistent hallucinations, delusions and severe cognitive dysfunction. - **Extreme mood swings**: Users may experience dramatic mood swings, including extreme excitement, panic, anxiety and even aggressive behavior. 3. **More severe physiological reactions**: - **Strong cardiovascular effects**: Some synthetic drugs can cause a sudden increase in heart rate and blood pressure, increasing the risk of heart attack and stroke. - **Overstimulation of the nervous system**: Synthetic stimulants (such as new psychoactive substances MDPV, α-PVP) may cause severe excitement, tremors, convulsions, and even epileptic seizures. 4. **Higher addiction and tolerance**: - **Rapid development of dependence**: Due to the high potency of synthetic drugs, users may develop psychological and physiological dependence more quickly, increasing the difficulty of withdrawal and relapse. - **Increased tolerance**: Frequent use may cause users to need larger doses to achieve the same effect, further increasing health risks. 5. **Unstable impurities and purity**: - **Unknown ingredients**: Synthetic drugs are often mixed with other unknown or harmful chemicals, increasing unpredictable side effects and health hazards. - **Uneven dosage**: Due to the lack of supervision in production and distribution, the purity and dosage of synthetic drugs are often unstable, increasing the risk of overdose. 6. **Legal and social impact**: - **Rapidly changing chemical structures**: Drug manufacturers often adjust the chemical structure of synthetic drugs to circumvent legal supervision, resulting in the emergence of new drugs, making it difficult for public health and law enforcement agencies to respond in a timely manner, increasing social harm. **Summary**: New synthetic drugs are generally more harmful to users and society than traditional drugs due to their high potency, stronger and unpredictable effects, and higher health and social risks. Prevention and education are essential to reduce the abuse of synthetic drugs.