Using gene editing technology to design microorganisms that have a lasting effect on human decision-making and emotional control is a highly complex and ethically controversial topic. In theory, gene editing (such as CRISPR-Cas9) can be used to modify the genome of microorganisms so that they can produce specific chemicals that may affect the host's nervous system and emotions. For example, some microorganisms can be designed to produce molecules that affect neurotransmitters, such as dopamine, serotonin, etc., which are closely related to emotional regulation and decision-making processes. However, there are many challenges and problems in such research: 1. **Biosafety**: The modified microorganisms may have unexpected effects on the ecosystem or human health. 2. **Ethical issues**: The manipulation of human emotions and decision-making has raised ethical controversies, especially those related to free will and individual autonomy. 3. **Complexity**: The biological basis of emotions and decision-making is very complex, involving not only a single neurotransmitter, but also closely related to genetics, environment, and personal experience. Simply affecting these processes through the regulation of microorganisms may not be very reliable. 4. **Long-term effects and dependence**: Even if a certain microorganism can be designed, its long-term effects and potential dependence are still unknown. In general, although such a proposal has certain feasibility from a scientific point of view, it needs to undergo rigorous research, evaluation and ethical review before implementation.