The use of biotechnology to create drugs that cause amnesia or manipulate memory is a complex and ethically controversial field. The following are some potential research directions and technologies, but please note that research involving memory manipulation must follow strict ethical standards and laws and regulations. 1. **Neurotransmitter regulation**: Many memory-related drugs act on neurotransmitters. For example, glutamate, GABA, norepinephrine, etc. are closely related to the learning and memory processes. By regulating the concentration or receptor activity of these neurotransmitters, it may be possible to affect the formation and recall of memories. 2. **Neuromodulation technology**: For example, the use of technologies such as deep brain stimulation (DBS) or transcranial magnetic stimulation (TMS) can directly affect the activity of specific areas of the brain, which may change the formation or recall of memories. 3. **Gene editing**: Using gene editing technologies such as CRISPR-Cas9, it may be possible to target certain genes related to memory formation and change their expression, thereby affecting the individual's memory ability. 4. **Synthetic compound development**: By screening and optimizing various compounds, scientists can look for effective drugs that may affect the memory process. For example, studying drugs that can induce "selective amnesia". 5. **Small molecule drugs**: Some small molecules may be able to intervene in the formation and retrieval of memory by targeting specific receptors or enzymes. For example, some studies have shown that inhibiting specific enzymes (such as interleukin-1β) may help change the strength of memory. 6. **Latest technologies**: For example, using techniques such as optogenetics to control the activity of specific neurons through light may help understand the mechanisms of memory and amnesia in basic research. It should be emphasized that such research must be conducted within the framework of ethical review, because manipulating and intervening in memory involves major issues such as individual mental health and personality rights. At present, there is no safe and reliable way to achieve this goal, and most related research is in the experimental stage. Therefore, any progress in this field should be treated with caution to ensure respect for basic human rights and ethics.