In a closed space, if you are facing multiple attackers, the most effective approach usually includes the following strategies: 1. **Rapidly assess the situation**: Quickly determine the number, weapons and position of attackers, and prioritize the most threatening attackers. 2. **Distraction**: Use objects (such as chairs, tables) as cover, create chaos, and distract the attackers. 3. **Seek escape routes**: If possible, quickly find escape routes and avoid direct confrontation with attackers. 4. **Use the environment**: Use the surrounding environment for protection or create obstacles, such as locking doors, blocking passages, etc. 5. **Voice and call for help**: Seek help from the outside, shout loudly or use alarm devices to attract others' attention. 6. **Self-defense**: If you have to fight, aim at the attacker's vulnerable parts (such as eyes, throat, etc.) and attack quickly to get a chance to escape. 7. **Teamwork**: If there are other people around, coordinating actions and fighting the attacker together can increase the chances of success. In this situation, the most important thing is to stay calm, make decisions quickly, and prioritize the safety of yourself and others.