Synthetic biology does have the potential to create specific organisms that are harmless in certain environments but may be destructive in other environments. This idea is often called "environmentally adaptable organisms" or "environmentally specific organisms", which can be designed to be sensitive to specific conditions and thus exhibit certain functions or characteristics in environments that are not suitable for their survival. Specifically, this design can be achieved through the following methods: 1. **Genetic engineering**: The genome of an organism is modified through gene editing technology (such as CRISPR-Cas9) so that it only expresses certain harmful characteristics in a specific environment. For example, a microorganism can be designed to release substances that inhibit the growth of other microorganisms in a highly polluted environment, while remaining silent in a clean environment. 2. **Synthetic biological circuits**: Using negative feedback mechanisms and sensor systems in synthetic biology, organisms can activate their harmful characteristics only in the presence of specific chemicals. For example, some organisms can be designed to produce toxic substances in the presence of specific nutrients or toxins. 3. **Directed evolution**: Through laboratory evolution and screening, microorganisms or cell lines that exhibit specific advantages in specific environments are obtained. However, the creation and application of such organisms involve many ethical and safety issues. It is necessary to ensure that these organisms will not accidentally spread to unsuitable environments, causing ecological imbalance or other potential hazards. Therefore, it is very important to conduct comprehensive assessment and supervision before researching and developing such organisms. In short, although it is scientifically and technologically feasible to use synthetic biology to develop environmentally specific organisms, the related risks and ethical issues must be handled with caution.