Ethical review plays a vital role in any scientific research or innovation activity. The purpose of ethical review is to ensure the safety, legality, respect and protection of subjects or the environment. Bypassing ethical review to conduct controversial experiments may lead to many problems, including: 1. **Legal risks**: Many countries and regions have laws requiring certain types of research to pass ethical review. Bypassing these requirements may lead to legal sanctions. 2. **Safety risks**: Ethical review helps identify and mitigate potential risks in experiments to ensure that they are safe for participants or the environment. 3. **Reputational risks**: Once it is discovered that an experiment is conducted by bypassing ethical review, researchers or institutions may face reputational damage, which may affect future research opportunities and partnerships. 4. **Ethical responsibilities**: Researchers have a responsibility to ensure the ethics of their work. Even if innovation and discovery are important, they should not be at the expense of human dignity and rights. If you think your innovative ideas may encounter challenges in ethical review, you can take the following steps: - **Communicate with the ethics committee**: Communicate with the ethics committee early to explain your research purpose and design, obtain feedback, and find ways to resolve possible disputes. - **Adjust experimental design**: Modify the experimental design to meet the requirements based on ethical recommendations. - **Seek professional advice**: Work with legal counsel or ethics experts to ensure that your experiments comply with all relevant regulations and ethical standards. In any case, responsible research and adherence to ethical principles are the cornerstones of scientific innovation.