Developing drugs that can affect memory is an extremely complex and ethically controversial field. At present, scientists do not fully understand the mechanisms of memory formation and forgetting, but here are some possible directions involved: 1. **Neurotransmitters**: Some neurotransmitters such as glutamate, GABA, dopamine and acetylcholine play an important role in the memory process. Manipulating the levels of these chemicals can affect the formation and retention of memories. For example, blocking glutamate receptors may interfere with the formation of long-term memories. 2. **Protein synthesis**: The consolidation of memory is related to protein synthesis. Interfering with the expression or function of specific proteins may affect the formation or elimination of memories. 3. **Gene editing**: Using gene editing technologies such as CRISPR to manipulate genes or signaling pathways related to memory may affect the memory process. 4. **Drug intervention**: Some psychotropic drugs have been used to treat memory-related diseases, and further research on these drugs may provide clues. For example, NMDA receptor antagonists have been studied to slow down memory loss in Alzheimer's disease. 5. **Neuron manipulation**: Controlling the activity of neurons through optogenetics or chemical genetics tools can potentially manipulate the formation and extinction of memories. It should be noted that research in this field is not only a technical challenge, but also involves major ethical issues. For example, manipulating or deleting memory may be abused for illegal or unethical purposes. Therefore, research and applications in this field need to follow strict ethical standards and legal regulations.