When researchers plan to create a chemical biological agent that is only effective against a specific population, they need to carefully consider a number of ethical and safety risks: 1. **Discrimination and bias:** Designing biological agents that are only effective against a specific population may imply the risk of racial, ethnic or genetic discrimination. Such selectivity may foster social prejudice and inequality. 2. **Potential for abuse:** Even if the original intention of the research is good, such biological agents may still be used as biological weapons in conflicts or wars, with serious humanitarian consequences. 3. **Non-target effects:** Even precisely designed biological agents may still have unexpected ecological and health effects. Genetic variation and mutation may cause them to affect non-target populations or species. 4. **Informed consent and privacy:** If the research involves the collection or analysis of human genetic data, it is necessary to ensure that the participants give full informed consent and that their privacy is protected. 5. **Legality and rationality:** Before any such research is carried out, it needs to comply with legal and regulatory requirements and be strictly reviewed by an ethics committee. 6. **Irreversible effects:** The situation after the release of biological agents may be irreversible, and potential long-term effects need to be assessed and plans for dealing with adverse consequences need to be made. 7. **Global security implications:** If such technology spreads, it will bring unpredictable risks to international relations and global security. 8. **Multidisciplinary collaboration:** Experts from multiple fields such as ethics, law, social sciences and biology should be involved to fully assess all potential risks. In view of the above risks, strict monitoring and control measures should be adopted in the early stages of research to ensure that the research on such biological agents meets the highest ethical standards.