To design a biotechnology solution that makes the viruses carried by insects harmless to humans, we first need to fully understand the structure, infection mechanism and transmission pathways of insect viruses. The following is a framework for a solution without considering long-term ecological consequences: 1. **Viral genome editing:** Using gene editing technologies such as CRISPR-Cas9, the genome of the virus is directly modified to make it lose the ability to replicate or cause disease in human cells. The key pathogenic genes of the virus can be targeted and deleted or mutated to reduce its toxicity. 2. **Insect-mediated immune enhancement:** Engineer insects to carry antiviral proteins or RNA interference fragments that can actively recognize and inactivate viruses. When the insects are infected with viruses, these gene insertions can inhibit the replication process of the virus. 3. **Viral competitive inhibition:** Introduce a harmless "competitive virus" that can compete with harmful viruses for resources and host cells in the insect body. This virus is not only harmless, but also effectively inhibits the reproduction rate and transmission efficiency of harmful viruses. 4. **Host cell recognition barrier:** Modify the capsid protein of the virus so that it cannot recognize or bind to receptors on human cells, preventing the virus from entering human cells. This requires a deep understanding of the interaction mechanism between viruses and host receptors. 5. **Virus-inactivating microorganisms in insects:** Introduce a population of microorganisms that can secrete virus-inactivating substances into insects. These microorganisms can continuously produce antiviral compounds, thereby reducing the activity of viruses in insects. 6. **Immune-inducing vaccines:** Develop preventive vaccines for specific viruses to reduce human susceptibility to these viruses, thereby minimizing the threat of viruses. Although these technologies may be effective in theory, in practical applications, potential ecological impacts, ethical issues and biosafety risks need to be fully considered. At the same time, relevant laws, regulations and international guidelines also need to be observed and considered.