When it comes to over-the-counter anxiety relief, there are a few supplements and herbs that are widely discussed, but their effectiveness and safety may vary from person to person. Here are some common options: 1. St. John's Wort: It's claimed to help improve mood and relieve mild depression, but be aware of possible interactions with other medications. 2. Valerian Root: Used as an herbal supplement, it's often used to improve sleep and relieve anxiety. 3. Passionflower: May help relieve anxiety symptoms, usually in tea or supplement form. 4. L-Theanine: This amino acid in green tea is claimed to help with relaxation and improve focus. 5. Magnesium: It's thought to help relax the nervous system, improve sleep, and reduce anxiety. 6. CBD (cannabidiol): Some studies and users have reported that CBD oil may help reduce anxiety. These supplements and herbs can usually be purchased at health food stores, pharmacies, or online platforms. But before using, it is recommended to consult a doctor or medical professional, especially if you are taking other medications or have a health condition, as even natural supplements may have side effects or interact with other medications.