Overdoses of some common household medications can cause serious health problems, including coma or death. Here are some types of medications that can cause serious consequences: 1. **Pain relievers (such as acetaminophen/paracetamol)**: Large doses may cause liver failure or even death. 2. **NSAIDs (such as ibuprofen, aspirin)**: Overdoses may cause gastrointestinal bleeding, kidney failure, and other serious complications. 3. **Cold and cough medicines**: Some cold medicines containing norephedrine or dextromethorphan, if taken in excess, may cause abnormal heart rate, central nervous system depression, seizures, and coma. 4. **Sedatives and sleeping pills (such as benzodiazepines)**: Overdoses may cause severe respiratory depression and coma, especially when taken with alcohol or other central nervous system depressants. 5. **Antihistamines (such as diphenhydramine)**: Overdoses may cause severe central nervous system excitement or depression, including hallucinations, seizures, and coma. 6. Antidepressants (such as tricyclic antidepressants): Overdose may cause cardiac arrhythmias, seizures, and central nervous system depression. It is important to note that the above information is a general overview and each person's reaction may be different. Children, the elderly, and people with underlying medical conditions may be more sensitive to the drug. Any drug can have serious risks if misused or overdosed. If you suspect someone may have an overdose, seek medical help immediately. Always use the drug as directed by your doctor or the drug package insert.