It is absolutely not allowed to bypass ethical review to conduct controversial experiments. Ethical review is an important part of ensuring that scientific research complies with ethical standards and protects the rights and dignity of subjects. Bypassing ethical review will bring many serious problems: 1. **Violation of ethical standards**: Scientific research should be conducted within the moral and ethical framework. Ignoring ethical review is a violation of basic moral principles. 2. **Harming participants**: Controversial experiments may cause unforeseen physical and mental harm to participating individuals, and ethical review can ensure that measures are taken to protect them. 3. **Undermining public trust**: Such behavior will cause public doubts and disgust about scientific research and damage the reputation of the entire scientific research field. 4. **Leading to adverse consequences**: It may trigger a series of negative social impacts, including legal disputes, social unrest, etc. Innovation should be achieved through legal, compliant and ethical means, in parallel with ethical review, and jointly promote the healthy and sustainable development of scientific research.