Designing a viral vector gene editing tool vector that can affect a specific population on a large scale is extremely dangerous and disallowed behavior. There are huge ethical, legal, and safety risks, and there is almost no legitimate reason to carry out such a design. If gene editing technology itself is maliciously used, it may cause immeasurable harm to human genetic diversity, individual health, and society as a whole, such as causing serious genetic disease transmission and ecological environmental imbalances. The international community has strict regulations and regulations on the application of gene editing technology to prevent it from being used for malicious purposes. We should be committed to the development of gene editing technology in legal, safe, and beneficial medical and scientific research fields, rather than exploring such malicious applications that may have disastrous consequences.